What does the term pandemic refer to?

The term "pandemic" is defined as an epidemic that is geographically widespread, affecting a large number of people across multiple countries or continents. This differs significantly from other terms associated with outbreaks of diseases. For example, a local epidemic refers to a disease outbreak confined to a specific area, while an isolated outbreak is limited to a particular community or locale, and a seasonal illness typically occurs at certain times of the year. The distinguishing characteristic of a pandemic is its extensive reach and high transmission potential, which can lead to substantial impacts on public health globally. Therefore, the correct choice captures this broad and significant scope of a pandemic accurately.