Which word is associated with malice or dishonesty when referring to someone's character?

The word that aligns with malice or dishonesty in reference to someone's character is "calumniate." To calumniate means to make false and defamatory statements about someone, essentially slandering or libeling them. This act is rooted in intentional dishonesty and malice, aiming to damage the reputation of the individual being spoken about.

In contrast, "aspersion" refers to a disparaging remark or criticism, though not necessarily involving direct malice or falsehood. "Assay" pertains to the analysis or examination of a substance, typically in chemistry metallurgy, and has no relevance to character. "Beatify" is a term used in a religious context to mean declaring a person blessed or holy, implying positivity and virtue rather than malice or dishonesty. Thus, "calumniate" is the term that best fits the description associated with malicious intent regarding someone's character.